ETIOLOGICAL FACTORS AS A RISK FOR THE DEVELOPMENT OF ALLERGIC CONTACT DERMATITIS

Abstract

This article examines the etiology of allergic contact dermatitis.

Allergic contact dermatitis is a delayed-type IV hypersensitivity reaction that occurs upon contact with an allergen in hypersensitive individuals due to the activation of allergen-specific T cells.

It can be associated with both occupational and non-occupational exposure to allergens and accounts for approximately 90% of occupational skin diseases. Diagnosis requires patch testing with suspected allergens. Metals, particularly nickel, fragrance compounds, isothiazolinones, and paraphenylenediamine are the most common allergens that patients react to during patch testing.